Macular Pigment and Visual Function in Patients With Glaucoma: The San Diego Macular Pigment Study
نویسندگان
چکیده
منابع مشابه
Macular pigment is associated with glare-affected visual function and central visual field loss in glaucoma.
AIM To evaluate the relationship between macular pigment optical density (MPOD) and glare disability in open-angle glaucoma. METHODS A cross-sectional analysis of baseline data (88 subjects; median age, 67 (range 36-84) years) collected during the Macular Pigment and Glaucoma Trial (ISRCTN registry number: 56985060). MPOD at 0.25°, 0.5° and 1° of retinal eccentricity was measured using custom...
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BACKGROUND The macula (central retina) contains a yellow pigment, comprising the dietary carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin, known as macular pigment (MP). The concentrations of MP's constituent carotenoids in retina and brain tissue correlate, and there is a biologically-plausible rationale, supported by emerging evidence, that MP's constituent carotenoids are also imp...
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PURPOSE To investigate the relationship between macular pigment (MP) and visual function in subjects with early age-related macular degeneration (AMD). METHODS 121 subjects with early AMD enrolled as part of the Central Retinal Enrichment Supplementation Trial (CREST; ISRCTN13894787) were assessed using a range of psychophysical measures of visual function, including best corrected visual acu...
متن کاملMacular pigment and age related macular degeneration.
The present concepts of the pathogenesis of AMD include cumulative light damage by oxidative processes in the macular photoreceptors as environmental co-factor for the development of AMD. The direct causative connection of this hypothesis has still to be established but wide circumstantial evidence from epidemiological and basic scientific investigations are strongly supportive. Macular pigment...
متن کاملMacular pigment distribution in Stargardt macular disease.
PURPOSE To investigate macular pigment optical density (MPOD) and distribution in patients with Stargardt disease. METHODS Prospective observational case series. The study included 13 eyes of 13 consecutive patients. A modified confocal scanning laser ophthalmoscope (SLO, Heidelberg, Germany) was used for MPOD measurement. It calculated the MPOD at 0.5° of the center of the fovea, and MPOD in...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2018
ISSN: 1552-5783
DOI: 10.1167/iovs.18-24170